On the verge of death and enduring a serious wound, a man stumbles into a hospital, only to be saved by a sexy nurse named Yu Yagami. He is moved to the special ward where he is interviewed by the beautiful hospital director Reika Goei. Thereupon, she asks him to become a test subject for a new virility drug. With no parents, siblings, or a girlfriend in his life, he agrees to become a test subject. Immediately, Yu Yagami gets assigned to be his "personal" nurse. No one had any idea what a sex-changed deviant they were going to create, or what would happen next.